The Insectian Cocoon was a powerful weapon that was sewn by Arachnia in episode 27 of Fullmetal Alchemist: Reborn. Her intention was for her eldest daughter, Beautifly, to enter it and "shed the rest of her mortal beauty" so that she can complete her metamorphosis. Beautifly refused, and when Arachnia tried to force her transformation, she ran away. 

The Insectian Cocoon
Beautifly's Cocoon (FMA)
Vital statistics
Type Weapon
Effects Turns whoever enters it into a powerful insectoid monster
Source Arachnia
Cost to buy No price
Cost to sell No price

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